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Scientists led by Prof David Ginsburg of the University of Michiganís Howard Hughes Medical Institute inhibited the action of a gene responsible for transporting a protein that interferes with the ability of the liver to remove cholesterol from the blood in mice. Trapping the destructive protein where it couldnít harm receptors responsible for removing cholesterol preserved the liver cellsí capacity to clear plasma cholesterol from the blood, but did not appear to otherwise affect the health of the mice.
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