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February 16 2013

Scientists Engineer Mice That Can't Feel The Cold

In the depths of winter, nothing seems as tempting as the inability to feel how frostbitten your toes are. Thanks to a group of neuroscientists at the University of California, that could soon be possible (though maybe not advisable.) They were able to identify the specific neurons that transmit cold sensations and shut them off in adult mice.

In his previous research, neurobiologist David McKemy had found a link between the ability to sense cold and the receptor for menthol (the ingredient that makes mint cool), a protein called TRPM8.

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