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For centuries, the fate of the original Otomí inhabitants of Xaltocan, the capital of a pre-Aztec Mexican city-state, has remained unknown. Researchers have long wondered whether they assimilated with the Aztecs or abandoned the town altogether.

According to new anthropological research from The University of Texas at Austin, Wichita State University and Washington State University, the answers may lie in DNA. Following this line of evidence, the researchers theorize that some original Otomies, possibly elite rulers, may have fled the town. Their exodus may have led to the reorganization of the original residents within Xaltocan, or to the influx of new residents, who may have intermarried with the Otomí population.