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Grocery store aisles are awash in foods and beverages that contain high-fructose corn syrup. It is common in sodas and crops up in everything from ketchup to snack bars. This cheap sweetener has been an increasingly popular additive in recent decades and has often been fingered as a driver of the obesity epidemic.

These fears may be well founded. Fructose, a new study finds, has a marked affect on the brain region that regulates appetite, suggesting that corn syrup and other forms of fructose might encourage over-eating to a greater degree than glucose. Table sugar has both fructose and glucose, but high-fructose corn syrup, as the name suggests, contains a higher proportion of fructose.