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Since the 1960s, manufacturers have widely used the chemical bisphenol-A (BPA) in plastics and food packaging. Only recently, though, have scientists begun thoroughly looking into how the compound might affect human health—and what they’ve found has been a cause for concern.

Starting in 2006, a series of studies, mostly in mice, indicated that the chemical might act as an endocrine disruptor (by mimicking the hormone estrogen), cause problems during development and potentially affect the reproductive system, reducing fertility. After a 2010 Food and Drug Administration report warned that the compound could pose an especially hazardous risk for fetuses, infants and young children, BPA-free water bottles and food containers started flying off the shelves. In July, the FDA banned the use of BPA in baby bottles and sippy cups, but the chemical is still present in aluminum cans, containers of baby formula and other packaging materials.